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Powerful protection
for your best friend

Our content and products are for informational purposes only.
GreatPetCare does not provide medical advice, diagnosis, or treatment.

NexGard® PLUS

(afoxolaner, moxidectin, and pyrantel chewable tablets)

All dogs are at risk of coming into contact with common parasites such as fleas, ticks, heartworms, and intestinal worms. Year-round use of broad-spectrum preventative medication can help guard against uncomfortable symptoms and dangerous diseases that can harm your pet.

A combination product such as NexGard PLUS provides internal and external parasite control in a tasty beef-flavored soft chew to make dosing easier for dogs and pet parents alike. Ask your vet about “one-and-done” monthly protection to see if it’s the right fit for your canine companion!¹

Please see Full Prescribing Information.²


NexGard® COMBO

(esafoxolaner, eprinomectin, and praziquantel topical solution)

Regardless of if they’re indoor or outdoor pets, cats are always at risk of parasites. Other animals in the home can bring critters indoors, rodents cats catch can transmit hookworms or roundworms, and ticks can even hitch a ride on your clothing after a day outside. That’s why it’s important to ensure your cat receives consistent parasite control all year long.

Formulated specially for cats, NexGard COMBO is the first and only monthly feline parasiticide that kills fleas and ticks, prevents heartworm disease, and treats and controls hookworms, roundworms, and tapeworms. Ask your vet about “one-and-done” topical protection to see if it’s the right fit.³

Please see Full Prescribing Information.⁴


NexGard®

(afoxolaner)

Fleas and ticks can be found in any season, all across the country – and no matter where you live, routine parasite control products are essential to protect your pet from discomfort and risky diseases such as Lyme.

NexGard was the first flea and tick product of its kind to market, and over 300 million monthly doses have been prescribed to date. Available in a delicious beef soft chew, it starts killing fleas within hours and continues to target both fleas and ticks all month long. Ask your vet about the #1 dog-preferred flea and tick chew to see if it’s right for your pet!⁵

Please see Full Prescribing Information.⁶


Heartgard® Plus

(ivermectin/pyrantel)

Heartworm disease has been diagnosed in every state across the country, and just a single bite from an infected mosquito can spread this potentially deadly illness to your pet. Common intestinal parasites such as hookworms and roundworms can also pose serious threat to your dog’s health, so it’s important to provide your furry family member with regular, ongoing preventative medication to avoid these risks.

With more than 30 years of proven protection, Heartgard Plus is the #1 dog-preferred oral heartworm chew. Its real-beef flavor makes dosing easier and more enjoyable, and it prevents heartworm disease while also treating and controlling three species of hookworms and two species of roundworms – every month, all year long.⁷

Please see Full Prescribing Information.⁸


IMPORTANT SAFETY INFORMATION:

NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. The most frequently reported adverse reactions include diarrhea, vomiting, lethargy, and itching. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infection prior to starting a preventive. For more details, click here for full prescribing information.

NexGard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is for topical use only in cats. Safe for use in cats and kittens 8 weeks of age or older, weighing 1.8 pounds or more. Use with caution in cats with a history of seizures or neurologic disorders. The most frequently reported adverse reactions include vomiting, application site reactions, lethargy, and anorexia. If ingested, hypersalivation may occur. Avoid direct contact with application site until visibly dry. For more details, click here for full prescribing information.

NexGard® (afoxolaner) is for use in dogs only. Safe for use in puppies 8 weeks of age or older, weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more details, click here for full prescribing information.

Following the use of Heartgard® Plus (ivermectin/pyrantel) in dogs, digestive and neurologic side effects and itching have been reported. Safe for puppies 6 weeks of age or older with no weight restrictions. All dogs should be tested for heartworm infection before starting a preventive program. For more details, click here for full prescribing information.


Sources:
1. NexGard PLUS product website. https://nexgardforpets.com/nexgard-plus. Accessed online March 11, 2025.
2. For full product information, including risks and/or side effects, visit https://nexgardforpets.com/sites/default/files/2023-07/NGP_COMBO_Interactive_PI_v2.pdf
3. NexGard COMBO product website. https://nexgardforpets.com/nexgard-combo. Accessed online March 11, 2025.
4. For full product information, including risks and/or side effects, visit https://docs.boehringer-ingelheim.com/AH/NexGard_COMBO_PI.pdf
5. NexGard product website. https://nexgardforpets.com/nexgard. Accessed online March 11, 2025.
6. For full product information, including risks and/or side effects, visit https://docs.boehringer-ingelheim.com/AH/NexGard_Mono_PI.pdf
7. Heartgard Plus product website. https://heartgard.com/. Accessed online March 11, 2025.
8. For full product information, including risks and/or side effects, visit https://docs.boehringer-ingelheim.com/AH/HEARTGARD_Plus_PI.pdf

NexGard PLUS, NexGard COMBO, NexGard, and Heartgard Plus are registered trademarks of Boehringer Ingelheim Animal Health France, used under license. Trademarks are the property of their respective owners. Prescription products featured require approval from your veterinarian. Important safety information for all products listed can be found on individual storefront product description pages.